French Researchers Discover a New Component in Blood – Gilmore Health News

French researchers discovered the presence of complete and functional mitochondria in the bloodstream. Ultimately, this discovery may lead to better diagnosis, monitoring, and treatment of many diseases, including some cancers.

Blood Cells

Our blood consists of red and white blood cells and platelets bathed in a liquid known as plasma. But the blood is also composed of complete and functional mitochondria researchers at the Inserm of the University of Montpellier and the Montpellier Cancer Institute revealed in a study published on January 19 in The Faseb Journal. These organelles play a key role in maintaining the lipid content and good ion concentrations necessary for physiological communication, in supplying the energy needed for blood circulation, in supporting the transport of glucose and insulin and in eliminating potential health risks.

Read Also: Mitochondrial Damage Can Cause Osteoporosis According to Study

They also have the peculiarity of having their own genome. The genome is transmitted exclusively by the mother and differs from the DNA in the nucleus. Until now, mitochondria have only been found outside cells in special cases, released by platelets into the extracellular space. In the long term, these results, unprecedented in physiology, pave the way for new therapeutic paths.

In the past, research has shown that a healthy persons blood plasma contains up to 50,000 times more mitochondrial DNA than nuclear DNA. To try to detect and quantify it in the blood, the researchers here had the idea of protecting it in a stable structure. Then they analyzed about 100 blood plasma samples.

Using a highly sensitive detection method called genetic amplification, which allows for direct measurement of minimal amounts of DNA, they discovered the presence of structures in the bloodstream that contain the intact, functional mitochondrial genomes. If you look at the high number of extracellular mitochondria we find in the blood, we wonder why this was not discovered earlier, says Professor Alain R. Thierry, who led the research.

Read Also: FIT A New Cancer Self-Test Kit That Can Save Lives

In the blood, these mitochondria could be involved in physiological and/or pathological processes that require communication between cells, such as inflammatory mechanisms, the researchers argue. In particular, recent studies have shown that certain cells can exchange mitochondria, such as stem cells with damaged cells. The extracellular mitochondria could perform various tasks as messengers for the whole body, explains Alain R. Thierry.

Ultimately, this discovery could lead to better diagnosis, monitoring or treatment of certain diseases.

The research team is now investigating the extracellular mitochondria as biomarkers in non-invasive prenatal diagnosis and cancer. Further research is needed to assess the impact and potential implications of this discovery in terms of cellular communication, inflammation and clinical applications, the researchers conclude.

Read Also: Genomic Analysis May Detect Lung Cancer Before It Even Develops

Since mitochondria play a key role in regulating the bodys major metabolic pathways, their destruction or weakening can lead to serious complications such as multiple sclerosis, autism, bipolar disorder, chronic fatigue syndrome, type 2 diabetes, heart disease, and cancer.

When the mitochondrial DNA is altered, the risk of cancer increases. When too many free radicals are produced, mitochondria create oxidative stress that prevents antioxidants from defending the body against cancer. In the past, researchers have found that it is mainly lung, breast and kidney cell carcinomas that have increased as a result of these mutations.

https://onlinelibrary.wiley.com/doi/full/10.1096/fj.201901917RR

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French Researchers Discover a New Component in Blood - Gilmore Health News

Frances CNES calls for long-term collaboration with ISRO on human spaceflight – Economic Times

Jean-Yves Le Gall, president, CNES, Frances national centre for space studies, has called for cooperation between France and India in human spaceflight mission.

He said the CNESs support for the Gaganyaan missions is the first step towards future collaboration on development of Indias planned space station.

The CNES president highlighted how France has acquired more than 40 years of experience in human spaceflight and developed highly sophisticated facilities in this field in Toulouse, such as the CADMOS (centre for the development of microgravity applications and space operations) and the MEDES (space medicine and physiology institute), backed by world-renowned French expertise in space medicine.

Gall, who was the guest of honour at the international Human Spaceflight Symposium organized in Bangalore, said CNES and ISROs teams have finalized drafting of the agreement to provide services at CADMOS and MEDES in collaboration with ESAs European Astronaut Centre (EAC) and potentially at Novespace to conduct experiments and training on parabolic flights aboard the Air Zero G.

We want cooperation between France and India in human spaceflight to evolve into a long-term partnership along the same lines as our 15-year collaboration on climate-monitoring satellites and 50 years working together on launchers, said Gall.

CNES and ISRO had signed an agreement in 2018, when the Gaganyaan programme was first announced, to train Indian flight physicians provide training in France and the use of equipment developed by CNES by the countrys future astronauts.

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Frances CNES calls for long-term collaboration with ISRO on human spaceflight - Economic Times

Hon. Dr. Dale Layman, 2019 Humanitarian of the Year and Founder of Robowatch LLC, Sits Down Again with the Top 100 Registry Inc. for a Spotlight…

PR.com2020-01-23

Joliet, IL, January 23, 2020 --(PR.com)-- The Honorable Dr. Dale Pierre Layman, AS, BS, MS, EdS, PhD #1, PhD #2, Grand PhD in Medicine, MOIF, FABI, DG, DDG, LPIBA, IOM, AdVMed, AGE, is the Founder and President of Robowatch, LLC. (The website is at http://www.robowatch.info) Robowatch is an international non-profit group whose main purpose is to keep a watchful human eye on the fast-moving developments occurring in the fields of robotics, computing and Artificial Intelligence (A.I.) industries.

The Hon. Layman was the very first person in his family to attend college. In 1968, he was awarded an Associate of Science (AS) degree in Life Science, from Lake Michigan College. The same year, he won a Michigan Public Junior College Transfer Scholarship to the University of Michigan in Ann Arbor. In 1971, he received an Interdepartmental B.S. with Distinction, in Anthropology - Zoology, from the University of Michigan. From 1971 to 1972, Layman was employed as a Histological Technician in the Department of Neuropathology, at the University of Michigan Medical School. From 1972 to 1974, he was attending classes and serving as a Teaching Fellow, in the Physiology Department of the U of M Medical School, for which he was awarded an MS, in 1974.

From Fall of 1974 to Spring of 1975, Dr. Layman was hired under the Federal CETA Program, for one year, as an Instructor in the Biology Department, at Lake Superior State College. A major career achievement occurred in the Fall of 1975. It was then, that Dr. Layman was hired as a full-time, permanent Instructor in the Natural Science Department of Joliet Junior College, Joliet, Illinois. He taught Human Anatomy & Physiology, and Medical Terminology, for 32 years full-time, before retiring in 2007. He then returned and taught part-time, from 2008 to 2010. While employed, he wrote six textbooks in his field, was selected as a Notable Author by Text and Academic Authors, and served as a Council Member on their Governing Board.

While he was still teaching at Joliet Junior College, Dr. Layman ardently kept going and going for more schooling. In 1979, he received an Ed.S. (Educational Specialist) degree in Physiology and Health Science, from Ball State University. Dale received his first Ph.D. from the University of Illinois, in Health and Safety Studies, in 1986. In 2003, Dr. Layman received both a second Ph.D., as well as a Grand Ph.D. in Medicine, from the Academie Europeenne D'Informatisation (AEI) and the World Information Distributed University (WIDU). He also holds a Full Professorship in the World Information Distributed University, located in Brussels, Belgium. "Prof. Dale Pierre Layman is the First Grand Doctor of Philosophy in Medicine in the USA," the Grand Doctor's Committee stated. Grand PhD Vorontsov (under Secretary-General of the United Nations), also noted that, "He was the first, who has formulated the global problem: From Homo Sapiens to Robo Sapiens, and he has grounded a danger of this potentially irreversible process to Natural Man."

Dr. Layman has received numerous published accolades over the years, and his biography has appeared in many Who's Who-type publications. For example, in 2018, he was the Cover Feature for the Top 100 Registry of Business Leaders and Professionals. On the cover, he was shown falling into a Deep Black Hole in Cyberspace, clutching a human skull in his right hand, and The Great 2045 "Robo-" Death Clock in his left hand. He implored, "Please Help Us Save Mankind!" This was followed by his 2019 Cover Feature for this distinguished publication, where he was dressed in costume as Elad, the Extra-terrestrial, who begged, "Please Help Us Save Mankind!!!" Elad (Dr. Layman's alter-ego) was praised as Humanitarian Of The Year, and he was featured in a video from the Top 100. Now, in the Year 2020, Layman also appears in a longer video, including Elad, who tells his Tale of Woe, as he is the last surviving member of his race, from the robot-dead Planet, Terra. Additionally, he will be the 2020 Cover Feature.

Most recently, Dr. Layman attended the 40th Annual Economic Outlook (January 22, 2020), sponsored by The Executives' Club of Chicago, at the Hyatt Regency hotel. Before the program, Dr. Layman approached many other attendees and passed out his business cards, while holding up that very morning's issue of USA Today. The front of the Money section flashed this article by Edward Baig: "AI - - 2020 and Beyond: Where AI Is Going." One quote from the article states, "What pretty much everyone agrees on is that AI will make a profound difference through the next decade and beyond, during which we may see a further blurring between human and machine."

Dr. Layman has been taking additional classes at Joliet Junior College - trying to become a polymath - while also earning a second membership in Phi Theta Kappa.

Watch Dr. Layman's Full Interview Here

Contact Information:

Top 100 Registry Inc.

David Lerner

855-785-2514

Contact via Email

http://www.top100registry.com

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Hon. Dr. Dale Layman, 2019 Humanitarian of the Year and Founder of Robowatch LLC, Sits Down Again with the Top 100 Registry Inc. for a Spotlight...

Wouldn’t have won Nobel Prize if based in India: Abhijit Banerjee – India Today

It isn't that there's no good talent in India, but a certain kind of system is needed, MIT professor and renowned economist Abhijit Banerjee said in Jaipur on Sunday.

Photo: Mail Today

Indian-American economist Abhijit Banerjee says he wouldn't have been able to win a Nobel Prize if he were based in his country of origin.

It isn't that there's no good talent in India, but a certain kind of system is needed, he said today at a literature festival here.

It's not possible for a single individual to achieve it, Abhijit Banerjee said, explaining that a lot of work for which he got credit was done by others.

Born in Mumbai, Abhijit Banerjee was educated at the University of Calcutta and Jawaharlal Nehru University. He received his PhD from Harvard University and is a professor at the Massachussetts Institute of Technology (MIT).

In 2019, he shared the Sveriges Riksbank Prize in Economic Sciences in Memory of Alfred Nobel with his wife Esther Duflo and Michael Kremer. They were given the award "for their experimental approach to alleviating global poverty.

The prize in economics isn't technically a Nobel. It wasn't established by Alfred Nobel's will, which says his wealth should be distributed to those making contributions to humankind in the fields of physiology or medicine, literature, physics, chemistry and peace.

Nonetheless, the economics prize is among the most coveted honours in the field of economic sciences.

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Wouldn't have won Nobel Prize if based in India: Abhijit Banerjee - India Today

Anatomy of a Lie: How Iran Covered Up the Downing of an Airliner – The New York Times

When the Revolutionary Guards officer spotted what he thought was an unidentified aircraft near Tehrans international airport, he had seconds to decide whether to pull the trigger.

Iran had just fired a barrage of ballistic missiles at American forces, the country was on high alert for an American counterattack, and the Iranian military was warning of incoming cruise missiles.

The officer tried to reach the command center for authorization to shoot but couldnt get through. So he fired an antiaircraft missile. Then another.

The plane, which turned out to be a Ukrainian jetliner with 176 people on board, crashed and exploded in a ball of fire.

Within minutes, the top commanders of Irans Revolutionary Guards realized what they had done. And at that moment, they began to cover it up.

For days, they refused to tell even President Hassan Rouhani, whose government was publicly denying that the plane had been shot down. When they finally told him, he gave them an ultimatum: come clean or he would resign.

Only then, 72 hours after the plane crashed, did Irans supreme leader, Ayatollah Ali Khamenei, step in and order the government to acknowledge its fatal mistake.

The New York Times pieced together a chronology of those three days by interviewing Iranian diplomats, current and former government officials, ranking members of the Revolutionary Guards and people close to the supreme leaders inner circle and by examining official public statements and state media reports.

The reporting exposes the governments behind-the-scenes debate over covering up Irans responsibility for the crash while shocked Iranians, grieving relatives and countries with citizens aboard the plane waited for the truth.

The new details also demonstrate the outsize power of the Islamic Revolutionary Guards Corps, which effectively sidelined the elected government in a moment of national crisis, and could deepen what many Iranians already see as a crisis of legitimacy for the Guards and the government.

The bitter divisions in Irans government persist and are bound to affect the investigation into the crash, negotiations over compensation and the unresolved debate over accountability.

Around midnight on Jan. 7, as Iran was preparing to launch a ballistic-missile attack on American military posts in Iraq, senior members of the Islamic Revolutionary Guards Corps deployed mobile antiaircraft defense units around a sensitive military area near Tehrans Imam Khomeini Airport.

Iran was about to retaliate for the American drone strike that had killed Irans top military commander, Gen. Qassim Suleimani, in Baghdad five days earlier, and the military was bracing for an American counterstrike. The armed forces were on at war status, the highest alert level.

But in a tragic miscalculation, the government continued to allow civilian commercial flights to land and take off from the Tehran airport.

Gen. Amir Ali Hajizadeh, commander of the Guards Aerospace Force, said later that his units had asked officials in Tehran to close Irans airspace and ground all flights, to no avail.

Iranian officials feared that shutting down the airport would create mass panic that war with the United States was imminent, members of the Guards and other officials told The Times. They also hoped that the presence of passenger jets could act as a deterrent against an American attack on the airport or the nearby military base, effectively turning planeloads of unsuspecting travelers into human shields.

After Irans missile attack began, the central air defense command issued an alert that American warplanes had taken off from the United Arab Emirates and that cruise missiles were headed toward Iran.

The officer on the missile launcher near the airport heard the warnings but did not hear a later message that the cruise missile alert was a false alarm.

The warning about American warplanes may have also been wrong. United States military officials have said that no American planes were in or near Iranian airspace that night.

When the officer spotted the Ukrainian jet, he sought permission to fire. But he was unable to communicate with his commanders because the network had been disrupted or jammed, General Hajizadeh said later.

The officer, who has not been publicly identified, fired two missiles, less than 30 seconds apart.

General Hajizadeh, who was in western Iran supervising the attack on the Americans, received a phone call with the news.

I called the officials and told them this has happened and its highly possible we hit our own plane, he said later in a televised statement.

By the time General Hajizadeh arrived in Tehran, he had informed Irans top three military commanders: Maj. Gen. Abdolrahim Mousavi, the armys commander in chief, who is also the chief of the central air defense command; Maj. Gen. Mohammad Bagheri, chief of staff of the Armed Forces; and Maj. Gen. Hossein Salami, commander in chief of the Revolutionary Guards.

The Revolutionary Guards, an elite force charged with defending Irans clerical rule at home and abroad, is separate from the regular army and answers only to the supreme leader. At this point, the leaders of both militaries knew the truth.

General Hajizadeh advised the generals not to tell the rank-and-file air defense units for fear that it could hamper their ability to react quickly if the United States did attack.

It was for the benefit of our national security because then our air defense system would be compromised, Mr. Hajizadeh said in an interview with Iranian news media this week. The ranks would be suspicious of everything.

The military leaders created a secret investigative committee drawn from the Guards aerospace forces, from the armys air defense, and from intelligence and cyberexperts. The committee and the officers involved in the shooting were sequestered and ordered not to speak to anyone.

The committee examined data from the airport, the flight path, radar networks, and alerts and messages from the missile operator and central command. Witnesses the officer who had pulled the trigger, his supervisors and everyone involved were interrogated for hours.

The group also investigated the possibility that the United States or Israel may have hacked Irans defense system or jammed the airwaves.

By Wednesday night, the committee had concluded that the plane was shot down because of human error.

We were not confident about what happened until Wednesday around sunset, General Salami, the commander in chief of the Guards, said later in a televised address to the Parliament. Our investigative team concluded then that the plane crashed because of human errors.

Ayatollah Khamenei was informed. But they still did not inform the president, other elected officials or the public.

Senior commanders discussed keeping the shooting secret until the planes black boxes the flight data and cockpit voice recorders were examined and formal aviation investigations completed, according to members of the Guards, diplomats and officials with knowledge of the deliberations. That process could take months, they argued, and it would buy time to manage the domestic and international fallout that would ensue when the truth came out.

The government had violently crushed an anti-government uprising in November. But the American killing of General Suleimani, followed by the strikes against the United States, had turned public opinion around. Iranians were galvanized in a moment of national unity.

The authorities feared that admitting to shooting down the passenger plane would undercut that momentum and prompt a new wave of anti-government protests.

They advocated covering it up because they thought the country couldnt handle more crisis, said a ranking member of the Guards who, like others interviewed for this article, spoke on condition of anonymity to discuss internal deliberations. At the end, safeguarding the Islamic Republic is our ultimate goal, at any cost.

That evening, the spokesman for the Joint Armed Forces, Brig. Gen. Abolfazl Shekarchi, told Iranian news media that suggestions that missiles struck the plane were an absolute lie.

On Thursday, as Ukrainian investigators began to arrive in Tehran, Western officials were saying publicly that they had evidence that Iran had accidentally shot down the plane.

A chorus of senior Iranian officials from the director of civil aviation to the chief government spokesman issued statement after statement rejecting the allegations, their claims amplified on state media.

The suggestion that Iran would shoot down a passenger plane was a Western plot, they said, psychological warfare aimed at weakening Iran just as it had exercised its military muscle against the United States.

But in private, government officials were alarmed and questioning whether there was any truth to the Western claims. Mr. Rouhani, a seasoned military strategist himself, and his foreign minister, Javad Zarif, deflected phone calls from world leaders and foreign ministers seeking answers. Ignorant of what their own military had done, they had none to give.

Domestically, public pressure was building for the government to address the allegations.

Among the planes passengers were some of Irans best and brightest. They included prominent scientists and physicians, dozens of Irans top young scholars and graduates of elite universities, and six gold and silver medal winners of international physics and math Olympiads.

There were two newlywed couples who had traveled from Canada to Tehran for their weddings just days earlier. There were families and young children.

Their relatives demanded answers. Iranian social media began to explode with emotional commentary, some accusing Iran of murdering its own citizens and others calling such allegations treason.

Persian-language satellite channels operating from abroad, the main source of news for most Iranians, broadcast blanket coverage of the crash, including reports from Western governments that Iran had shot down the plane.

Mr. Rouhani tried several times to call military commanders, officials said, but they did not return his calls. Members of his government called their contacts in the military and were told the allegations were false. Irans civil aviation agency called military officials with similar results.

Thursday was frantic, Ali Rabiei, the government spokesman, said later in a news conference. The government made back-to-back phone calls and contacted the armed forces asking what happened, and the answer to all the questions was that no missile had been fired.

On Friday morning, Mr. Rabiei issued a statement saying the allegation that Iran had shot down the plane was a big lie.

Several hours later, the nations top military commanders called a private meeting and told Mr. Rouhani the truth.

Mr. Rouhani was livid, according to officials close to him. He demanded that Iran immediately announce that it had made a tragic mistake and accept the consequences.

The military officials pushed back, arguing that the fallout could destabilize the country.

Mr. Rouhani threatened to resign.

Canada, which had the most foreign citizens on board the plane, and the United States, which as Boeings home country was invited to investigate the crash, would eventually reveal their evidence, Mr. Rouhani said. The damage to Irans reputation and the public trust in the government would create an enormous crisis at a time when Iran could not bear more pressure.

As the standoff escalated, a member of Ayatollah Khameneis inner circle who was in the meeting informed the supreme leader. The ayatollah sent a message back to the group, ordering the government to prepare a public statement acknowledging what had happened.

Mr. Rouhani briefed a few senior members of his government. They were rattled.

Mr. Rabiei, the government spokesman who had issued a denial just that morning, broke down. Abbas Abdi, a prominent critic of Irans clerical establishment, said that when he spoke to Mr. Rabiei that evening, Mr. Rabiei was distraught and crying.

Everything is a lie, Mr. Rabiei said, according to Mr. Abdi. The whole thing is a lie. What should I do? My honor is gone.

Mr. Abdi said the governments actions had gone far beyond just a lie.

There was a systematic cover-up at the highest levels that makes it impossible to get out of this crisis, he said.

Irans National Security Council held an emergency meeting and drafted two statements, the first to be issued by the Joint Armed Forces followed by a second one from Mr. Rouhani.

As they debated the wording, some suggested claiming that the United States or Israel may have contributed to the accident by jamming Irans radars or hacking its communications networks.

But the military commanders opposed it. General Hajizadeh said the shame of human error paled compared with admitting his air defense system was vulnerable to hacking by the enemy.

Irans Civil Aviation Agency later said that it had found no evidence of jamming or hacking.

At 7 a.m., the military released a statement admitting that Iran had shot down the plane because of human error.

The bombshell revelation has not ended the division within the government. The Revolutionary Guards want to pin the blame on those involved in firing the missiles and be done with it, officials said. The missile operator and up to 10 others have been arrested but officials have not identified them or said whether they had been charged.

Mr. Rouhani has demanded a broader accounting, including an investigation of the entire chain of command. The Guards accepting responsibility, he said, is the first step and needs to be completed with other steps. His spokesman and lawmakers have demanded to know why Mr. Rouhani was not immediately informed.

Mr. Rouhani touched on that concern when he put out his statement an hour and 15 minutes later. The first line said that he had found out about the investigative committees conclusion about cause of the crash a few hours ago.

It was a stunning admission, an acknowledgment that even the nations highest elected official had been shut out from the truth, and that as Iranians, and the world, turned to the government for answers, it had peddled lies.

What we thought was news was a lie. What we thought was a lie was news, said Hesamedin Ashna, Mr. Rouhanis top adviser, on Twitter. Why? Why? Beware of cover-ups and military rule.

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Anatomy of a Lie: How Iran Covered Up the Downing of an Airliner - The New York Times

Grey’s Anatomy Sparked Major Backlash Over the Confusing ‘Station 19’ Crossover – countryliving.com

Greys Anatomy has finally returned from its winter hiatus after leaving us all holding a collective breath after a grippingand potentially fatalfall finale.

Fortunately, the series is back on the air to finally address the aftermath of the car that plowed into Joes Bar, putting several of our favorite doctors, and later Station 19 firefighters, in grave danger.

ABC used the drama to create one one, big two-hour crossover episode with both the medical mainstay and its popular spinoff. At a glance, two hours of our favorite hotshots sounds too good to be true. However, some Greys fans lashed out on Twitter for a few different reasons.

The first was that Grey's and Station 19 are swapping times, with Station 19 now airing first on Thursdays at 8 p.m. EST followed by Grey's at 9 p.m.

Others were upset that they missed the first half of the two-episode event, unaware that they needed to tune in for both.

But even more seemed enraged over feeling forced to watch the spinoff in order to understand the new Greys that followed.

Since most of the overlapping events happened during the first hour as firefighters worked to free the victims from the rubble, it does sound pretty imperative to watch both.

Those who have never watched Station 19 seemed particularly annoyed, since they had to sit through a show in which they aren't familiar with the characters and arent super invested in.

It's not the first time the shows have overlapped, and it looks like more crossovers are to come. Krista Vernoff, the showrunner of both series, told Variety that plots will continue to intersect throughout the season. However, it sounds like it will be on a smaller scale, as Krista said that characters in Station 19 might become patients in the following episode of Greys (hence the time change).

Some fans picked up on the storyline possibilities with the shift in schedule as well.

Either way, it sounds like Thursday nights just got even more interesting!

Link:
Grey's Anatomy Sparked Major Backlash Over the Confusing 'Station 19' Crossover - countryliving.com

Bowen Yang of S.N.L. Is a Smash. And a Mensch. – The New York Times

Once the therapy was complete, his father let Bowen go to New York University, where his sister, already a student there, could chaperone him.

The irony of it all is I went to the gayest undergrad in the country, he says, smiling, about his alma mater, which he mocks in stand-up routines as a real estate firm, celebrity day care center and a multicomplex head-shot studio.

I spent freshman year trying straightness on for size and failing miserably, he says. I sort of tricked myself into having a crush on a girl but it was just kind of a weird, weird, weird pit stop. Then I would look at a boy and be like, Oh, I want to talk to him. Mr. Yang has a tattoo on his arm, drawn by a nonbinary Chinese tattoo artist, with ancient signets. They represent his parents last names. He never got mad at them.

I had this second coming out with them while I was in college and went through this whole flare-up again with them, where they couldnt accept it, Mr. Yang says. And then eventually, I just got to this place of standing firm and being like, This is sort of a fixed point, you guys. I cant really do anything about this. So either you meet me here or you dont meet me.

It never got to the point of, I wont come home again. I was just like, Im not going to argue with them. Like my dad every now and then will be like, So, when are you going to meet a girl? And Ill just calmly be like, Dad, its not going to happen. I mean, its O.K. Both my parents are doing a lot of work to just try to understand and I cant rush them. I cant resent them for not arriving at any place sooner than theyre able to get there.

His parents and sister proudly came to his first show as a cast member last fall.

Bowen went to pre-med classes, got a chemistry degree, and took the MCAT, partly influenced by the character played by his idol Sandra Oh on Greys Anatomy.

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Bowen Yang of S.N.L. Is a Smash. And a Mensch. - The New York Times

Did Amelia Owen’s Baby on "Grey’s Anatomy"? It is a total mess – Daily Gaming Worlld

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It wouldnt be another season of Greys Anatomy without anything going wrong in Amelias life. Shes got a bad hand in life right now and although Link did everything right, it could turn out that her unborn baby is Owens instead of that of her good-natured younger friend. In the autumn finale of season 16, she found that she was more advanced in pregnancy than originally thought, which means that her relationship with Link and her relationship with Owen overlap somewhat.

Now everyone is talking about whether Amelia Owens will have a baby or not. At this point, the baby could be either Link or Owens, but in either case, the conversations Amelia has to have to determine paternity will be uncomfortable at best. Hopefully it will work out for them someday, but it will definitely not be an easy way to get there.

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Did Amelia Owen's Baby on "Grey's Anatomy"? It is a total mess - Daily Gaming Worlld

The Facts: Women, Age and Fertility – THISDAY Newspapers

AGE RELATED INFERTILITY(ARI)Part 1

Scientific evidence shows thatin women,fertility peaks in mid 20sand starts a steep decline in mid 30s despitethisso many people still postponestarting a family.Somemodern womenwant tofocus on education,buildtheircareer,and of course some wantstable financial base, or theright manmay not be coming,so the need to wait forthe perfect partner. Whatever the reasonsfor delaying parenthood are, it is however unfortunate that the natural clock doesnt stop ticking hence the human body keeps aging inevitably.It is a fact that in todays society, inability to conceive due to age is becoming much more common because women arewaiting until their 30s and 40s to have children. Although many women are healthier in later lifeand taking better care of themselves, this doesnot stopthe natural age-related decline in fertility. Recent reports from the European Society of Human Reproduction and Embryology (ESHRE) haveshown that more women are delaying childbearing at the present time than previously. This trend is expected to cause a corresponding rise in the mean age at which women first present with infertility and thisbringsusto the discussion for this week:AGE RELATED INFERTILITYas it affects both males and females.

WHAT IS AGE RELATED INFERTILITY: This is the decline in fertilitythat comeswith age, seen in bothmen and women.It is a known fact thatage relatedInfertilityaffects both sexes, its effect ishoweverseen much earlier in women than in men. Women30years and abovehave reducedquantity and qualityof eggs in their ovaries while male fertility starts to decline after 40 years when sperm quality begins to decrease. Allthese automatically increasetheriskfor chromosomal abnormalities like having too many or too few chromosomes(aneuploidy)which might result in conditions suchas,implantation failure,Down syndromeandeven higher chances ofmiscarriages. Older women are alsomorelikely to have health problems that may interfere with fertility makingpregnancy and delivery of a live birth more difficult.

The Facts: Women, Age and Fertility

Womenin their 20shave a20-25% chance of achieving pregnancy during their ovulation period. This drops to15-20% for women between the ages of 31 years and 35 years and to less than 10% for women ages 35 years and older. By 40years womentypically only havea 5% and by 45-49 years a 1%chanceof becoming pregnant without fertility treatmentper month.

Women are born with all the eggs they will ever have, unlike men who typically make new sperm throughout their life. Each month many eggs begin to develop, onlyone or tworeaches maturation and eventually ovulates(releases), the others undergoa process called atresia (degeneration). This process occurs in intrauterine life(before birth), before puberty, and during a womans reproductive years, even while pregnant or on oral contraceptive.

This progressive loss of eggs over a lifespan results in low egg numbers(quantity)that resultin lower pregnancy rate beginning usually in the 40s. There is also a corresponding loss in the quality of the eggs over time. As eggs age,they becomeless able to fertilize or evenimplantnormallyand aremore likely to result in a pregnancy that miscarries.

In addition,for a variety of reasons theprocess is accelerated in somewomen whose egg quantity and quality is low at a muchyounger age e.g.those diagnosedwith Premature Ovarian Insufficiency (POI).

Although the average age of menopause (no remaining egg) is about 51years. The decrease in the ability to conceive due to low egg quality and quantity occurs long before,usually beginning in the 30s and becoming more pronounced in the early 40s.Womenin their late40s rarely have a spontaneous pregnancy and if so, one in three will miscarry. It is due to this sense of urgency that women 35 years and aboveshouldconsider visitingfertilityexpertsforevaluation and havetheir fertility profiling doneas soon as they suspectdifficulty becoming pregnant.

If a womans egg quality or egg number is lower than expected for her age, there may be a discoverable treatablecause.

Are thereotherfactors that can decrease ovarian functionin women apart from agesuch asEndometriosis,Severe pelvic adhesion,Previous chemotherapy or radiation,history of smoking, ovarian surgery or removal ofa portionor all of an ovaryor both, genetics (Turners syndrome)etc.

However, decreased ovarian functioncan also occur in women without these predisposing factors. The cause of an early loss of eggs in some women is sometimes not clear, but it is thought to be due togenetic factors with or without a family history of early menopause.

The rule of 3s- ifa healthy woman irrespective of age, has conceived and made it up the first trimester, her odds of the pregnancy resulting in a live birth are almost the same regardless of age. The chances of having a good outcome and a healthy baby are very high. Of course all routine testing are still recommended during prenatal care.

It isworthy ofnote that the process of egg loss happens at a predictable and steady rate even if a woman takes good care of her health and looks young physically.Both egg quantity and quality determines a womans ability to conceive and both are influenced by ageand it is important to note that pregnancy is often possible with the right combination of treatment by fertility specialists.

To be continued.

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The Facts: Women, Age and Fertility - THISDAY Newspapers

Highs and lows of human behavior in two great books: Bill Ruehlmanns picks – Daily Press

He entered the vault, its hundreds of large white steel cabinets standing in rows like sentries, and got to work. ... Quivering beneath his fingertips were a dozen Red-ruffed Fruitcrows, gathered by naturalists and biologists over hundreds of years from the forests and jungles of South America and fastidiously preserved by generations of curators for the benefit of future research. He unzipped the suitcase and began filling it with the birds, emptying one drawer after another. He didnt know exactly how many hed be able to fit into his suitcase, but he managed forty-seven of the museums forty-eight male specimens before wheeling his bag on to the next cabinet.

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Highs and lows of human behavior in two great books: Bill Ruehlmanns picks - Daily Press