IUMS Hosting Reproductive Health Congress – Financial Tribune

An international congress on reproductive health organized by the Iranian Society of Embryology & Reproductive Biology (ISERB) will be held April 19-21 at the Iran University of Medical Sciences in Tehran. The 2nd International Congress on Reproductive Health and Childbearing (ICRHC) will provide a platform for exchange of data, information and scientific ideas in the field, icrhc-iserb.ir website reported. Sixteen panels will be held during the 3-day event, including medication therapy to enhance sperm quality, sexual health and strategies to improve marital relationships, endometriosis and POS (polycystic ovarian syndrome) treatment, screening embryo health before implantation in infertility treatment, social aspects of assisted reproduction, availability of infertility medications in Iran and their levels of effectiveness, and stem cells. Health experts who will address the confab are head of Food and Drug Administration Rasoul Dinarvand, deputy health minister Reza Malekzadeh, head of Avicenna Infertility Treatment Center Behzad Qorbani, head of ISERB Mohammad Mehdi Akhundi, head of FDAs Food and Drug Control Labs Hossein Rastegar, and head of Royan Research Institute Hamid Gourabi. Participants include doctors in reproduction biology and medical sciences and clinical experts in gynecology, obstetrics and infertility, urology, endocrinology and metabolism as well as in nutrition, midwifery, nursing, laboratory science. Besides, experts in paramedical sciences, veterinary medicine, sociology, psychology, law and ethics and general practitioners, will attend the congress. Introducing the latest scientific achievements in the field of reproductive health, motivating researchers in different branches of biology to apply biotechnology in reproduction issues, training physicians in diagnosis and treatment of different diseases, and creating research teams for interdisciplinary research, are the main goals of the congress.

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IUMS Hosting Reproductive Health Congress - Financial Tribune

Obesity and Diabetes Might Be Treated by Targeting Two BAT Cell Receptors – Genetic Engineering & Biotechnology News (blog)

Researchers say they have discovered a way to increase the amount of metabolism-boosting brown adipose tissue (BAT) ("good" fat) by employing two receptors on BAT cells as potential therapeutic targets. Both receptors, TRPM8 and TRPP3, are associated with the creation of BAT in humans and may be activated by certain foods, and possibly the envisioned new drugs. This has implications for the treatment of obesity, diabetes, and related metabolic disorders.

"Our study establishes the potential of TRPM8 and TRPP3 as druggable targets involved in human brown adipogenesis, to develop substances that can modulate energy consumption in individuals and blood sugar control," said Michael Raghunath, M.D., Ph.D., a researcher involved in the work at the Department of Life Sciences and Facility Management, Center for Cell Biology and Tissue Engineering, Zurich University of Applied Sciences, in Zurich, Switzerland. "In the face of a growing number of diabetic and obese people, our work hopefully will contribute to the development of nonadrenergic stimulators of brown fat and the appreciation of functional food to influence brown fat physiology."

To make this discovery, Dr. Raghunath and colleagues, who published their study ("TRP Channels in Brown and White Adipogenesis from Human Progenitors: New Therapeutic Targets and the Caveats Associated with the Common Antibiotic, Streptomycin") in the FASEB Journal,used two types of precursor cells from human donors: bone marrow stem cells (MSCs) and subcutaneous belly fat cells. They induced these cells to become white or brown fat, and in parallel cultures the cells were allowed to remain undifferentiated.

All 27 transient receptor potential (TRP) channels were analyzed during the process. Some TRPs were never expressed, some were constantly present, and some only during brown fat cell differentiation. TRPM8 and TRPP3 were present at high levels in differentiated brown fat, but not in progenitor cells. To investigate the role of TRPM8, they used specific activator or inhibitors and found that stimulation of TRPM8 strongly supported browning, whereas presence of the inhibitors impeded it. The function of TRPP3 was tested by using genetic manipulation to eliminate its function, and this prevented the formation of brown fat, but not white fat.

"Just when one begins to think every door in the brown fat field has been opened, here comes the olfactory receptors axis," commented Thoru Pederson, Ph.D., Editor-in-Chief ofThe FASEB Journal. "If further studies link this to food recognition (and thus preferences), a major advance will have been made."

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Obesity and Diabetes Might Be Treated by Targeting Two BAT Cell Receptors - Genetic Engineering & Biotechnology News (blog)

Cornell Researcher Explains Mechanisms of Communication Between Cancer Cells – Cornell University The Cornell Daily Sun

12 hours ago Science By Jheel Shah | 12 hours ago

What do cells talk about? Years of research have shown us that cells secrete and receive chemical substances to interact with each other. Clearly chemicals play a major role in cell communication, but is there more to the language of cells?

Prof. Mingming Wu, biological and environmental engineering, and her colleagues research ways in which cells use their physical environment to communicate with each other. Specifically, cells placed in a matrix of microscopic fibers interact with these fibers to send out signals. As opposed to the chemical signals that have been thoroughly researched, these cells use the physical fibrous network around them to relay messages.

Studying such microscopic phenomena is challenging. To run experiments, Wu and Matthew Hall 16 used a cell tank, an aquarium of sorts. A synthetic gel containing cells was then placed into the tank. However, creating a gel that mimics the natural matrix found in animal tissues is difficult. Biological tissues do not resemble simple, crisscross, linear patterns as much as they resemble tangled spaghetti.

After creating the gel, the team then placed tumour cells in it to study their interactions with the matrix. To do so, fluorescent beads were added to the matrix fibers so as to make any physical changes apparent as well as aid calculations of the forces these cells exert. Their observations revealed that the tumour cells pulled on the fibres and used them to propel themselves forward. Such findings are important because they could help explain how malignant cancer cells move rapidly in the body.

It was harder than I thought, but I didnt think it was impossible. Sometimes the community tells you that this is way too hard but I was trained as a physicist so I thought if something exists you got to be able to measure it, Wu said.

Furthermore, the tumour cells seemed to use this pulling action to communicate with other cells in the vicinity. This communication seemed to increase significantly when there was more sugar in the matrix. Thus, patients with higher levels of sugar such as those with diabetes would have greater communication between cancer cells and possibly experience a faster progression of the disease.

Wu plans to study these mechanisms in more realistic conditions, especially in the presence of fluids as is the case in actual animal tissue. She hopes that their research will eventually help them predict the direction of movement of cancer cells. Such prediction methods would support research that aims to control their movement and restrict them to certain regions.

Wu also credits the interdisciplinary approach behind the study. Prof. Chung-Yuen Hui, mechanical and aerospace engineering, played a pivotal role in the theory behind the experiments.

I think that collaboration shows us that biological engineering is quite interdisciplinary, it is tough for one person to just sit there and do something. One really needs everyone to work together, Wu said.

Wus research brings together the fields of cellular biology, physics and bio engineering to provide insights into the different ways cells communicate with each other. In time, propelled by a deeper understanding of how cells, especially cancer cells, move around in the body, such research may lead to new tools in the ongoing fight against the disease.

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New cocktail encourages stem cell diversification – Laboratory News – Lab News

A team of international scientists have discovered a chemical cocktail that enables stem cells to regrow any type of tissue.

The study highlights how totipotent the ability to develop into the placenta and omnipotent stem cells can be derived from both human and mouse embryos. Modelling early development processes and diseases affecting embryo implantation are two techniques that could be improved as a result of this discovery.

Professor Carlos Izpisua Bemonte, from the Salk Institute and co-author of the paper published in Cell, said: During embryonic development, both the fertilised egg and its initial cells are considered totipotent, as they can give rise to all embryonic and extra-embryonic lineages. However, the capture of stem cells with such developmental potential in vitro has been a major challenge in stem cell biology. This is the first study reporting the derivation of a stable stem cell type that shows totipotent-like bi-developmental potential towards both embryonic and extra-embryonic lineages.

Before the cocktail was created, the scientists screened chemical compounds that support pluripotency, discovering a combination of four chemicals and a growth factor was most effective. The cocktail stabilised immature human pluripotent cells, enabling a greater possibility of creating chimeric cells in developing murine embryos.

With the same cocktail was applied to murine cells, the team found that the new stem cells could not only produce embryonic tissue, but also form extra-embryonic cells, which then became the placenta or amniotic sac. These new stem cells could give rise to an entire adult mouse, which the researchers have said is unprecedented and have called extended pluripotent stem (EPS) cells.

Jun Wu, a senior scientist at Salk and first author of the paper, said: The discovery of EPS cells provides a potential opportunity for developing a universal method to establish stem cells that have extended developmental potency in mammals. Importantly, the superior interspecies chimeric competency of EPS cells makes them especially valuable for studying development, evolution and human organ generation using a host animal species.

The researchers next step will be to test if these EPS cells could be used in transgenic animal models and creating replacement product organs. EPS cells could work in tandem with research published at the beginning of the year in Cell, on interspecies chimeras. The team reported their success in growing a rat pancreas, heart and eyes in a developing mouse. Human cells and tissues were also grown in early-stage pig and cattle embryo, showing that an animal host could maybe grow organs for transplant.

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New cocktail encourages stem cell diversification - Laboratory News - Lab News

Biochemistry Analyzer Market Forecast 2022: Global & Chinese Key … – MilTech

Biochemistry Analyzer Market report provides key statistics on the market status of the Biochemistry Analyzer Manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the Biochemistry Analyzer industry.

The Biochemistry Analyzer Market report delivers a basic overview of the industry including its definition, applications and manufacturing technology. Also, the Biochemistry Analyzer industry report explores the international and Chinese Major Market players in detail.

The Biochemistry Analyzer market report presents the company profile, product specifications, capacity, production value, Contact Information of manufacturer and market shares for each company.

Through the statistical analysis, the Biochemistry Analyzer market report depicts the global and Chinese total market of Biochemistry Analyzer industry including capacity, production, production value, cost/profit, supply/demand and Chinese import/export. The total market is further divided by company, by country, and by application/type for the competitive landscape analysis.

Get PDF Sample of Report @ http://www.360marketupdates.com/enquiry/request-sample/10512588

Table of Contents:

Chapter 1 Overview of Biochemistry Analyzer Market1.1 Brief Overview of Biochemistry Analyzer Industry 1.2 Development of Biochemistry Analyzer Market 1.3 Status of Biochemistry Analyzer Market

Chapter 2 Manufacturing Technology of Biochemistry Analyzer Industry2.1 Development of Biochemistry Analyzer Manufacturing Technology 2.2 Analysis of Biochemistry Analyzer Manufacturing Technology 2.3 Trends of Biochemistry Analyzer Manufacturing Technology

Chapter 3 Analysis of Global Biochemistry Analyzer Market Key Manufacturers3.1.1 Company Profile 3.1.2 Product Information 3.1.3 2012-2017 Production Information 3.1.4 Contact Information

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Chapter 4 2012-2017 Global and Chinese Biochemistry Analyzer Market4.1 2012-2017 Global Capacity, Production and Production Value of Biochemistry Analyzer Market 4.2 2012-2017 Global Cost and Profit of Biochemistry Analyzer Market 4.3 Market Comparison of Global and Chinese Biochemistry Analyzer Industry 4.4 2012-2017 Global and Chinese Supply and Consumption of Biochemistry Analyzer Market 4.5 2012-2017 Chinese Import and Export of Biochemistry Analyzer

Chapter 5 Market Status of Biochemistry Analyzer Industry5.1 Market Competition of Biochemistry Analyzer Industry by Company 5.2 Market Competition of Biochemistry Analyzer Industry by Country (USA, EU, Japan, Chinese etc.) 5.3 Market Analysis of Biochemistry Analyzer Consumption by Application/Type

Chapter 6 2017-2022 Market Forecast of Global and Chinese Biochemistry Analyzer Market6.1 2017-2022 Global and Chinese Capacity, Production, and Production Value of Biochemistry Analyzer market 6.2 2017-2022 Biochemistry Analyzer market Cost and Profit Estimation 6.3 2017-2022 Global and Chinese Biochemistry Analyzer Market Share 6.4 2017-2022 Global and Chinese Supply and Consumption of Biochemistry Analyzer 6.5 2017-2022 Chinese Import and Export of Biochemistry Analyzer

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In the end, the Biochemistry Analyzer market report makes some important proposals for a new project of Biochemistry Analyzer Industry before evaluating its feasibility. Overall, the report provides an in-depth insight of 2012-2022 global and Chinese Biochemistry Analyzer market covering all important parameters.

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Biochemistry Analyzer Market Forecast 2022: Global & Chinese Key ... - MilTech

Biochemistry Analyzers Market: Capacity, Production, Revenue … – MilTech

United States Biochemistry Analyzers market is valued at USD XX million in 2016 and is expected to reach USD XX million by the end of 2022, growing at a CAGR of XX% between 2016 and 2022.

Biochemistry Analyzers Market is expected to witness growth of international market with respect to advancements and innovations including development history, competitive analysis and regional development forecast.

The report starts with a basic Biochemistry Analyzers market overview. In this introductory section, the research report incorporates analysis of definitions, classifications, applications and industry chain structure.

Biochemistry Analyzers Market split by product type,with production, revenue, price, market share and growth rate of each type, can be divided into

Biochemistry Analyzers Market split by application,report focuses on consumption, market share and growth rate of Biochemistry Analyzers in each application and can be divided into

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To begin with, the report elaborates the Biochemistry Analyzers Market overview. Various definitions and classification of the industry, applications of the industry and chain structure are given. Present day status of the Biochemistry Analyzers Market in key regions is stated and industry policies and news are analysed.

Following are the key players covered in this Biochemistry Analyzers Market research report:

And Many Others

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After the basic information, the Biochemistry Analyzers Market report sheds light on the production. Production plants, their capacities, global production and revenue are studied. Also, the Biochemistry Analyzers Market growth in various regions and R&D status are also covered.

Following are Major Table of Content of Biochemistry Analyzers Industry:

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Scope of the Biochemistry Analyzers Industry on the basis of region:

Additionally, type wise and application wise consumption figures are also given. With the help of supply and consumption data, gap between these two is also explained.

To provide information on competitive landscape, this report includes detailed profiles of Biochemistry Analyzers Market key players. For each player, product details, capacity, price, cost, gross and revenue numbers are given. Their contact information is provided for better understanding.

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Biochemistry Analyzers Market: Capacity, Production, Revenue ... - MilTech

From Anatomy to 3D Printing: Art Inspires Life – American Council on Science and Health

Oscar Wilde believed Life imitates art far more than art imitates life. Upon viewing the accompanying video animation of the anatomical relationships of Pectoralis Major and Minor created by Dr. Raf Ratinam, I became truly inspired.

Inspired to write an article, even two. Inspired by the mastery of the complexity of the human formand, an artists understanding of it. Inspired to explore the possibilities of the endless meaningful and powerful ways to impact my chosen field of medicine. Ways that involve navigating traditional and outside-of-the-box realms. All carrying the potential to change the world.

So, I will let you be the judge of whether life influenced art or art influenced life. Isnt that the purpose of such endeavors anyway? To question. To propel. To push the envelope and advance thought. To spark innovation.

Anatomy is complex. Its intricate labyrinth is the source of our capacity to grasp and turn a door knob. Walk down the street. Carry on conversation. Compete in escalating physical and intellectual endeavors. Each well-positioned nerve, vessel and organ permits our ability to function and thrive.

Comprehension of 3D planes and a firm grasp of spatial relations is requisite to depicting it let alone performing advanced surgeries. But, those surgeons start somewhere and it isnt the operating room. Books and simulations and ever-advancing technologies are speedily disrupting the field whether it be in medical education or biomedical engineering, to name a few. The future is bright and without limitation.

As you can tell, my outlook was expanded and energized by this artists work. So, I reached out to him via social media to learn more about his path and plans. Dr. Ratinam was working as an animator (or artist) with the goal of getting a job at a company like Pixar (he loves Toy Story, Monsters Inc. and The Incredibles). Then, he was offered a place in Graduate Medicine at the University of Melbourne, obtaining his medical degree in 2009. After graduating, he became a surgical resident at Monash Health in Victoria, Australia. Now, he is pursuing his PhD in 3D Printing/Anatomy at The Centre for Human Anatomy Education Faculty of Medicine, Monash University.

According to Dr. Ratinam, his current academic focus looks at the potential uses of three-dimensional printing in surgery and surgical (simulation) training. We are looking at 3-D printing technology and seeing if it can be potentially altered to better suit its use in anatomy and surgical teaching. Through the Anatomy and Developmental Biology Department, he is assessing the usefulness of such technology in hand surgery. Formally trained in 2-D and 3-D computer animation, he works on a casual basis as a surgical illustrator creating 2D/3D illustrations and animations for consultant surgeons.

To appreciate the wide spectrum of opportunity such an integrated background can yield, review his publication in Innovations: Technology & Techniques in Cardiothoracic & Vascular Surgery by the International Society for Minimally Invasive Cardiothoracic Surgery. He was a co-author and drew the rendering that explains Modified Tightening for Figure-of-Eight Sternal Wiring Closure.

With certain open heart surgeries, the sternumthe bony column in the center of ones chestis drilled through from top to bottom. Unless you have been in those operative cases (which I have during a cardiothoracic surgical rotation years ago), a drawing like the one in that journal is invaluable and informative.

Teaching medical students particularly in human anatomy is Dr. Ratinams passion. Ultimately, his goal is to become an academic surgeon who is highly involved in the teaching of future doctors and surgeons and being involved in advancements in surgical simulation technology. I also have a strong interest in new virtual reality technologies. Additionally, his main aim for the rest of my professional life is to create an Atlas of Anatomy while becoming a general or plastic surgeon. Makes sense.

Enjoy his various pieces interwoven throughout this article (the other video is a portrait of Daenerys from Game of Thrones). Dr. Ratinam reminds us that there are many routes into any career path these days which is great. I feel that it brings people with unique skillsets into the classroom or clinic.

Though his unique educational background and training propel him to innumerable career choices, it is possible to be a surgical or medical illustrator without needing to go to medical school. Check back tomorrow where I discuss how to pursue that course in the United States in my follow-up article, 5 Fun Ways to Impact Medicine (Without Needing Medical School).

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From Anatomy to 3D Printing: Art Inspires Life - American Council on Science and Health

Is Cristina Coming Back to Grey’s Anatomy? | POPSUGAR … – POPSUGAR

How has Grey's Anatomy managed to survive without badass cardiothoracic surgeon Dr. Cristina Yang for the last three seasons? Well, the popular medical drama has devoted quite some time to exploring Meredith's often precarious yet devoted sisterly bonds to Maggie and Amelia. As much as we love this new dynamic, there's no one quite like Mer's unapologetic soul sister or "person," as Mer puts it. From the pilot episode to Cristina's departure in season 10, Meredith and Cristina grow together, rising through the ranks from clueless interns to fearless attendings as they support each other through the worst of times. And we really do mean the worst of times: shootings, plane crashes, you name it.

Last Summer, Sandra Oh, the talented actress behind Cristina, sparked some hope in Grey's fans. She tweeted a picture with her Grey's Anatomy ex-husband Kevin McKidd, who plays trauma surgeon Dr. Owen Hunt, and former Grey's Anatomy screenwriter Tony Phelan.

Was it a merely a benign gathering of old chums, or were they discussing some Grey's business? It's most likely the former, but no one ever really knows when it comes to Shondaland. After all, the show has featured cameos from past main cast actors, like Kate Walsh and Isaiah Washington. On the matter of Cristina's return, McKidd casually commented in a recent interview that he'd "love it if she came back," and that he thinks "she might eventually for fun, for maybe a couple of episodes."

With Amelia and Owen's marriage on the rocks in season 13, some of us are speculating that Oh may return to add a plot twist or some unprecedented drama. Cristina is killing it in her career right now in Switzerland, and we couldn't be happier for her . . . but we wouldn't necessarily object to her return.

While promoting her new comedy film Catfight on Access Hollywood Live, Oh said that she doesn't think she'll come back to Grey's Anatomy, but gave a more evasive and uncertain answer about the possibility of returning for the series finale. Hinting that she had previously talked to showrunner Shonda Rhimes about it, Oh said: "I just don't know. It would just have to feel right." That's not a no!

We don't definitively know whether or not Cristina will be coming back, but if Oh does come back, it'll likely be a cameo or guest star appearance rather than a recurring role. If you miss seeing Oh on prime-time television, she'll be guest starring as a social worker in a three-episode story arc in the ABC series American Crime. For now, we'll just be rewatching throwback Grey's episodes and crying over this brilliant character brought to life by Oh's tour-de-force performance.

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Anatomy of a Goal: Ola Kamara’s Equalizer – Massive Report – Massive Report

Welcome to the Anatomy of a Goal, where each week we dissect one goal (or near goal) from the previous weeks Columbus Crew SC match.

For Week 7 on the 2017 MLS Season, we take a look at Ola Kamaras 37th minute tap-in goal that put Crew SC level with Toronto FC at 1-1, as part of the 2-1 win on Saturday.

Heres a look at the finish from the Columbus striker.

In the 20th minute, Jozy Altidore put Toronto in the lead with a headed goal off a Victor Vazquez corner kick. Toronto controlled much of the first 37 minutes, but Columbus begun to settle down and get back into this match.

Kamaras equalizing goal begins with a TFC throw in. Toronto left center-back Justin Morrow had three options in the above photo: center midfielder Michael Bradley, left midfielder Raheem Edwards, and center midfielder Armando Cooper. An unmarked Bradley was probably the best option, but Morrow instead opted to make a short throw to Cooper. Morrows throw barely reached Cooper, who was easily dispossessed by Crew SC winger Niko Hansen.

Above, notice that Crew SC attacking midfielder Federico Higuain is moving ahead of Morrow even before Hansen receives the bad throw in.

Having received Morrows errant throw in, Hansen plays a quick, safe ball to Higuain. Like many goals, the Crew SC equalizer hangs multiple decisions. This finish is the direct result of the Black & Gold rookie making multiple good choices in his first start for the Columbus.

Here, Hansen could have played a quick square ball to Artur or a longer pass to Kamara, but he instead leaned on Crew SCs veteran playmaker and that decision resulted in the goal.

Immediately after Hansen passes to Higuain, he makes an overlapping run along the touchline, dragging Morrow with him. Higuain now has three options: an early through ball to a goal-bound Kamara; a difficult square pass, around Bradley, to Justin Meram; or to slowdown his run and make a pass to the overlapping Hansen.

Seeing Hansen beat Morrow, Cooper shifts off of Higuain and onto the winger. This small movement opens up a passing lane behind Cooper, and into the path of the speedy Hansen.

Niko continues his run at full pace, and Higuain plays an inch-perfect through ball behind Cooper and into the path of the Crew SC winger. Hansens speed sends him goal-bound with space between him and the next defender.

Having received the ball and beaten both Morrow and Cooper, Hansen now has three options. He can continue his dribble forward and force Toronto center-back, and Ohio native, Nick Hagglund to pick him up; he could play a difficult pass to Kamara, who would potentially have a shot on goal; or, he could play an easy pass into the path of Meram.

The Crew SC winger makes the wise decision to continue his dribble, driving himself closer to the goal and forcing Hagglund to leave Kamara, who is running the channel between the Toronto center backs, and open up space for a pass to the striker.

Again, Hansen has a decision to make. He could pass the ball into the path of Kamara, who is onside and heading toward the goal or he could play into the path of Meram, who is unmarked but somewhat shielded by Michael Bradley.

From this angle on the same play, you can better see why Hansen made the correct decision to slot the ball into Kamara. Here you can see that Bradley might have been able to get to a pass to Meram and that Kamara was onside and only marked from behind.

Hansen makes the decision to send Kamara in on goal with a pass through the legs of Hagglund. Notice that Hansen plays this ball on the ground rather than sending in a lofted cross. The distance to goal and angle here obviously ask for a low pass, but Crew SC teams of the past have tended to play those goal-entry-passes in the air, to the ghost of 2015s Kei Kamara.

From this angle, its hard to tell whether the Crew SC striker is onside.

From the side, its clear that Kamara has slowed his run just enough to stay onside. Rather than maintain his defensive run on Kamara, Toronto center-back Eriq Zavaleta has decided to drop off of the Crew SC striker, hastily trying to make an offside claim while also covering the onrushing Meram.

As Hansens pass speeds beneath Hagglunds legs, you can see that Merams continued run has put Zavaleta into the unenviable position of having to cover two players at once. Again, instead of staying with Kamara, Zavaleta halfheartedly pleads for offside while putting himself into the path of Meram.

Kamara receives the ball in the perfect position to tie the game up for Crew SC.

Findings:

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Anatomy of a Goal: Ola Kamara's Equalizer - Massive Report - Massive Report

Hundreds to take on marathon task of raising cancer centre funds – Daily Echo

MORE than 200 people will be taking part in ABP Southampton marathon runs to support a campaign to build a 25million state-of-the-art centre for cancer immunology.

As previously reported by the Echo, the project was launched by the University of Southampton to offer the chance for Hampshire cancer patients to undergo trials using revolutionary new medicines.

Just 4.5million is needed to finish the build of the trailblazing facility at Southampton General Hospital.

Now, 223 runners are hoping to reduce that total by lacing up their shoes and taking part in the ABP Southampton Marathon, Half Marathon and 10k this Sunday.

Professor Tim Elliott, director for the Centre for Cancer Immunology, said: It is wonderful to see such support for the campaign from both staff and students all around the university.

The construction of the centre is well underway but we still need another 4.5m towards our fundraising target to make it a reality.

All contributions make a real difference and we are so grateful to all those running for the campaign.

At last years event, 30 runners collectively raised more than 9,500 towards the centre.

The four-storey building will be home to world-class research facilities, a clinical trials unit, and a suite of molecular biology laboratories, where genetic engineering will be used to develop new vaccine and antibody constructs.

It will also house a pre-clinical immunology lab investigating the complex interaction of cancer and the immune system

The state-of-the-art centre will be the first of its kind in the UK - and bring 50 new jobs to the city.

The flagship purpose-built centre will also bring together world-leading specialists who will use world-class research facilities and laboratories to work on a new cure the disease.

University bosses also hope it could transform the city into a hub for world leading biomedicine research and attract pharmaceutical manufacturers to the region.

The ABP Southampton Marathon, half marathon and 10k will be held this Sunday.

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Hundreds to take on marathon task of raising cancer centre funds - Daily Echo